| Day | Week | Home | Result | Away |
|---|---|---|---|---|
| 2025-03-16 | 1 | Angel City | 1 - 1 | San Diego Wave |
| 2025-03-22 | 2 | San Diego Wave | 3 - 2 | Utah Royals |
| 2025-03-29 | 3 | Orlando Pride | 2 - 1 | San Diego Wave |
| 2025-04-12 | 4 | San Diego Wave | 0 - 2 | Kansas City Current |
| 2025-04-19 | 5 | Racing Louisville | 1 - 4 | San Diego Wave |
| 2025-04-26 | 6 | Chicago Stars | 0 - 3 | San Diego Wave |
| 2025-05-04 | 7 | San Diego Wave | 2 - 1 | Bay FC |
| 2025-05-10 | 8 | San Diego Wave | 1 - 1 | Portland Thorns |
| 2025-05-16 | 9 | Gotham FC | 0 - 1 | San Diego Wave |
| 2025-05-25 | 10 | San Diego Wave | 5 - 2 | North Carolina Courage |
| 2025-06-06 | 11 | San Diego Wave | 1 - 2 | Seattle Reign |
| 2025-06-13 | 12 | Houston Dash | 2 - 3 | San Diego Wave |
| 2025-06-22 | 13 | San Diego Wave | 0 - 0 | Washington Spirit |
| 2025-08-02 | 14 | North Carolina Courage | 0 - 0 | San Diego Wave |
| 2025-08-09 | 15 | San Diego Wave | 1 - 1 | Angel City |
| 2025-08-16 | 16 | Bay FC | 1 - 2 | San Diego Wave |
| 2025-08-24 | 17 | San Diego Wave | 0 - 1 | Racing Louisville |
| 2025-08-29 | 18 | Seattle Reign | 0 - 0 | San Diego Wave |
| 2025-09-07 | 19 | San Diego Wave | 0 - 3 | Houston Dash |
| 2025-09-12 | 20 | San Diego Wave | 0 - 2 | Gotham FC |
San Diego Wave
2025シーズン